Shlomo Melmed Selected Research

Neoplasms (Cancer)

5/2024	Hypopituitarism.
1/2022	Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours: a consensus statement.
1/2022	Pituitary Somatotroph Adenoma-derived Exosomes: Characterization of Nonhormonal Actions.
1/2022	GH and Senescence: A New Understanding of Adult GH Action.
1/2022	Molecular targets in acromegaly.
1/2022	Dural Invasion as a Marker of Aggressive Pituitary Adenomas.
11/2021	International Multicenter Validation Study of the SAGIT® Instrument in Acromegaly.
1/2021	Two Distinctive POMC Promoters Modify Gene Expression in Cushing Disease.
1/2021	EGFR/ErbB2-Targeting Lapatinib Therapy for Aggressive Prolactinomas.
11/2019	Growth hormone in the tumor microenvironment.

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Shlomo Melmed Research Topics

Disease

64	Neoplasms (Cancer) 05/2024 - 01/2000
58	Pituitary Neoplasms (Pituitary Adenoma) 01/2024 - 01/2000
46	Acromegaly 04/2024 - 01/2002
25	Adenoma (Adenomas) 01/2024 - 01/2000
14	Pituitary ACTH Hypersecretion 10/2023 - 11/2002
12	Prolactinoma (Prolactinomas) 03/2024 - 02/2003
10	Carcinogenesis 01/2022 - 01/2002
9	Growth Hormone-Secreting Pituitary Adenoma 01/2022 - 01/2000
6	ACTH-Secreting Pituitary Adenoma 10/2023 - 11/2002
6	Hyperplasia 10/2012 - 01/2002
5	Cushing Syndrome 01/2023 - 05/2011
3	Hypogonadism (Hypergonadotropic Hypogonadism) 05/2024 - 08/2014
3	Ataxia Telangiectasia (Louis Bar Syndrome) 02/2019 - 12/2012
3	Inflammation (Inflammations) 01/2019 - 05/2002
3	Carcinoid Tumor (Carcinoid) 09/2018 - 12/2007
2	Adrenal Insufficiency (Adrenal Gland Hypofunction) 05/2024 - 08/2014
2	Fibrosis (Cirrhosis) 03/2024 - 01/2022
2	Hyperprolactinemia 12/2023 - 07/2006
2	Neoplasm Metastasis (Metastasis) 01/2022 - 10/2003
2	Carcinoma (Carcinomatosis) 01/2021 - 05/2009
2	Body Weight (Weight, Body) 02/2017 - 08/2008
2	Injection Site Reaction 02/2016 - 09/2008
2	Chromosomal Instability (Chromosome Stability) 08/2013 - 12/2012
2	Colonic Neoplasms (Colon Cancer) 01/2011 - 03/2008
2	Pituitary Diseases (Disease, Anterior Pituitary) 03/2010 - 02/2008
2	Aneuploidy (Aneuploid) 11/2008 - 11/2003
2	Headache (Headaches) 09/2008 - 07/2006
2	Neuroendocrine Tumors (Neuroendocrine Tumor) 05/2008 - 12/2007
2	Hypopituitarism (Sheehan's Syndrome) 10/2003 - 05/2003
1	Communicable Diseases (Infectious Diseases) 05/2024
1	Hypothyroidism 05/2024
1	Hypophysitis 05/2024
1	Traumatic Brain Injuries (Traumatic Brain Injury) 05/2024

Drug/Important Bio-Agent (IBA)

36	Growth Hormone (Somatotropin)IBA 05/2024 - 01/2000
23	Insulin-Like Growth Factor I (IGF-1)IBA 11/2023 - 01/2002
22	Hormones (Hormone)IBA 05/2024 - 05/2003
20	LigandsIBA 10/2023 - 05/2003
19	Adrenocorticotropic Hormone (ACTH)FDA Link 10/2023 - 05/2002
18	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 02/2017 - 01/2000
16	Somatostatin Receptors (Somatostatin Receptor)IBA 10/2023 - 06/2004
15	ProlactinIBA 12/2023 - 01/2002
14	Octreotide (Sandostatin)FDA LinkGeneric 12/2022 - 01/2000
12	Messenger RNA (mRNA)IBA 01/2022 - 01/2000
10	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2003
9	Dopamine Agonists (Dopamine Agonist)IBA 03/2024 - 10/2003
9	SecurinIBA 12/2012 - 03/2003
8	lanreotide (Somatuline)FDA Link 01/2022 - 01/2002
7	Insulin-Like PeptidesIBA 04/2024 - 03/2008
7	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 01/2021 - 05/2011
6	Hydrocortisone (Cortisol)FDA LinkGeneric 10/2023 - 08/2014
6	Insulin (Novolin)FDA Link 10/2019 - 10/2006
5	Tyrosine Kinase InhibitorsIBA 01/2021 - 10/2011
5	pasireotideIBA 02/2017 - 06/2004
5	ErbB Receptors (EGF Receptor)IBA 02/2017 - 01/2006
5	Estrogens (Estrogen)FDA Link 10/2012 - 01/2002
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2003
4	Phosphotransferases (Kinase)IBA 01/2022 - 12/2012
4	pegvisomant FDA LinkGeneric 01/2020 - 01/2002
4	Dopamine (Intropin)FDA LinkGeneric 02/2017 - 11/2003
4	CorticosteroneIBA 02/2017 - 11/2002
4	Transcription Factors (Transcription Factor)IBA 06/2016 - 04/2010
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2015 - 10/2005
4	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 04/2014 - 04/2003
4	CytokinesIBA 03/2009 - 05/2002
3	Glucose (Dextrose)FDA LinkGeneric 04/2024 - 02/2009
3	RoscovitineIBA 01/2023 - 05/2011
3	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 12/2006
3	Lapatinib (GW572016)FDA Link 01/2021 - 01/2011
3	Gefitinib (Iressa)FDA Link 02/2017 - 08/2008
3	GlucocorticoidsIBA 07/2015 - 11/2002
3	somatostatin receptor 2IBA 01/2015 - 06/2004
3	Epidermal Growth Factor (EGF)IBA 04/2014 - 08/2008
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2008 - 10/2003
3	PlasticsIBA 03/2006 - 12/2003
3	Leukemia Inhibitory FactorIBA 03/2006 - 05/2002
2	Somatotropin Receptors (Growth Hormone Receptor)IBA 08/2023 - 10/2003
2	EnzymesIBA 01/2023 - 09/2008
2	Dopamine Receptors (Dopamine Receptor)IBA 01/2022 - 02/2017
2	Cyclin EIBA 07/2015 - 05/2011
2	ClusterinIBA 12/2012 - 03/2011
2	TBR-760IBA 10/2012 - 12/2007
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 05/2011 - 02/2006
2	Luteinizing Hormone (Lutropin)FDA LinkGeneric 05/2011 - 05/2003
2	Follicle Stimulating Hormone (Follitropin)FDA Link 05/2011 - 04/2008
2	SteroidsIBA 01/2010 - 09/2008
2	aryl hydrocarbon receptor-interacting proteinIBA 05/2007 - 12/2006
2	enhanced green fluorescent proteinIBA 10/2006 - 11/2003
2	Glycoproteins (Glycoprotein)IBA 10/2006 - 05/2005
2	Rosiglitazone (Avandia)FDA Link 05/2003 - 11/2002
2	ThiazolidinedionesIBA 05/2003 - 11/2002
2	PPAR gammaIBA 05/2003 - 11/2002
2	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 05/2003 - 11/2002
1	Arginine Vasopressin (Argipressin)IBA 05/2024

Therapy/Procedure

41	Therapeutics 04/2024 - 01/2000
5	Radiotherapy 12/2023 - 07/2005
5	Injections 10/2023 - 05/2008
5	Drug Therapy (Chemotherapy) 05/2011 - 03/2003
2	Adrenalectomy 10/2023 - 09/2018
2	Subcutaneous Injections 05/2003 - 11/2002
1	Immunotherapy 05/2024